Genetic Risk For Nicotine Dependence in the Cholinergic System and Activation of the Brain Reward System in Healthy Adolescents

Genetic variation in a genomic region on chromosome 15q25.1, which encodes the alpha5, alpha3, and beta4 subunits of the cholinergic nicotinic receptor genes, confers risk to smoking and nicotine dependence (ND). Neural reward-related responses have previously been identified as important factors in...

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Detalhes bibliográficos
Main Authors: Nees, F, Witt, S H, Lourdusamy, A, Vollstädt-Klein, S, Steiner, S, Poustka, L, Banaschewski, T, Barker, G J, Büchel, C, Conrod, P J, Frank, J, Gallinat, J, Garavan, H, Heinz, A, Ittermann, B, Loth, E, Mann, K, Artiges, E, Paus, T, Pausova, Z, Smolka, M N, Struve, M, Schumann, G, Rietschel, M, Flor, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773681/
https://ncbi.nlm.nih.gov/pubmed/23689675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.131
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