Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine

Acetyl-L-carnitine (ALC) is a naturally occurring molecule with an important role in cellular bioenergetics and as donor of acetyl groups to proteins, including NF-κB p65. In humans, exogenously administered ALC has been shown to be effective in mood disturbances, with a good tolerability profile. N...

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Detalhes bibliográficos
Main Authors: Cuccurazzu, Bruna, Bortolotto, Valeria, Valente, Maria Maddalena, Ubezio, Federica, Koverech, Aleardo, Canonico, Pier Luigi, Grilli, Mariagrazia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773672/
https://ncbi.nlm.nih.gov/pubmed/23670591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.121
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