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Unexpected requirement for ELMO1 in apoptotic germ cell clearance in vivo

Apoptosis and the subsequent clearance of these dying cells occur throughout development and adult life in many tissues. Failure to promptly clear apoptotic cells has been linked to many diseases(1-3). ELMO1 is an evolutionarily conserved cytoplasmic engulfment protein that functions downstream of t...

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Bibliografiska uppgifter
Huvudupphovsmän: Elliott, Michael R., Zheng, Shuqiu, Park, Daeho, Woodson, Robin I., Reardon, Michael A., Juncadella, Ignacio J., Kinchen, Jason M., Zhang, Jun, Lysiak, Jeffrey J., Ravichandran, Kodi S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773546/
https://ncbi.nlm.nih.gov/pubmed/20844538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09356
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