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A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats

Vaccines for opioid dependence may provide a treatment that would reduce or slow the distribution of the drug to brain, thus reducing the drug's reinforcing effects. We tested whether a conjugate vaccine against morphine (keyhole limpet hemocyanin-6-succinylmorphine; KLH-6-SM) administered to r...

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Detalhes bibliográficos
Main Authors: Kosten, Therese A., Shen, Xiaoyun Y., O'Malley, Patrick W., Kinsey, Berma M., Lykissa, Ernest D., Orson, Frank M., Kosten, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773503/
https://ncbi.nlm.nih.gov/pubmed/23739535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2013.05.012
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