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JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

Excessive fluoride may cause central nervous system (CNS) dysfunction, and oxidative stress is a recognized mode of action of fluoride toxicity. In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extrac...

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Autors principals: Yan, Ling, Liu, Shengnan, Wang, Chen, Wang, Fei, Song, Yingli, Yan, Nan, Xi, Shuhua, Liu, Ziyou, Sun, Guifan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773420/
https://ncbi.nlm.nih.gov/pubmed/24072958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/895975
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