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Effect of Temporally Patterned TNF-α Delivery on In Vitro Osteogenic Differentiation of Mesenchymal Stem Cells Cultured on Biodegradable Polymer Scaffolds
Recent insight into the critical role of pro-inflammatory cytokines, particularly tumor necrosis factor-α (TNF-α), in bone regeneration has heralded a new direction in the design of bone tissue engineering constructs. Previous studies have demonstrated that continuous delivery of 50 ng/ml TNF-α to m...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773264/ https://ncbi.nlm.nih.gov/pubmed/23746285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09205063.2013.803455 |
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