Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum: Laboratory investigation

OBJECT: Although several clinical trials utilizing the adeno-associated virus (AAV) type 2 serotype 2 (2/2) are now underway, it is unclear whether this particular serotype offers any advantage over others in terms of safety or efficiency when delivered directly to the CNS. METHODS: Recombinant AAV2...

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Main Authors: Sanchez, Carlos E., Tierney, Travis S., Gale, John T., Alavian, Kambiz N., Sahin, Ayguen, Lee, Jeng-Shin, Mulligan, Richard C., Carter, Bob S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773229/
https://ncbi.nlm.nih.gov/pubmed/20950087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2010.8.JNS091583
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