Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

The 70kD heat shock proteins (Hsp70s) are ubiquitous molecular chaperones essential for cellular protein folding and proteostasis. Each Hsp70 has two functional domains: a nucleotide-binding domain (NBD) that binds and hydrolyzes ATP, and a substrate-binding domain (SBD) that binds extended polypept...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Qi, Ruifeng, Sarbeng, Evans Boateng, Liu, Qun, Le, Katherine Quynh, Xu, Xinping, Xu, Hongya, Yang, Jiao, Wong, Jennifer Li, Vorvis, Christina, Hendrickson, Wayne A., Zhou, Lei, Liu, Qinglian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772632/
https://ncbi.nlm.nih.gov/pubmed/23708608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2583
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky