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Phosphorylation of Tip60 Tyrosine 327 by Abl Kinase Inhibits HAT Activity through Association with FE65

The transfer of acetyl groups from acetyl coenzyme A to the ε amino group of internal lysine residues is catalyzed by Tip60, which is in the MYST family of nuclear histone acetyltransferases (HATs). The tyrosine phosphorylation of Tip60 seems to be a unique modification. We present evidence that Tip...

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Detalhes bibliográficos
Main Authors: Shin, Sung Hwa, Kang, Sang Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772572/
https://ncbi.nlm.nih.gov/pubmed/24044023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X20130622002
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