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Quantitative full time course analysis of nonlinear enzyme cycling kinetics

Enzyme inhibition due to the reversible binding of reaction products is common and underlies the origins of negative feedback inhibition in many metabolic and signaling pathways. Product inhibition generates non-linearity in steady-state time courses of enzyme activity, which limits the utility of w...

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Detalhes bibliográficos
Main Authors: Cao, Wenxiang, De La Cruz, Enrique M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772379/
https://ncbi.nlm.nih.gov/pubmed/24029878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02658
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