A Pre-microRNA-149 (miR-149) Genetic Variation Affects miR-149 Maturation and Its Ability to Regulate the Puma Protein in Apoptosis

MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs that function as negative regulators of gene expression. They are transcribed from endogenous DNA and form hairpin structures (termed as pre-miRNAs) that are processed to form mature miRNAs. It remains largely unknown as to the molecular...

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Bibliografiska uppgifter
Huvudupphovsmän: Ding, Su-Ling, Wang, Jian-Xun, Jiao, Jian-Qin, Tu, Xin, Wang, Qing, Liu, Fang, Li, Qian, Gao, Jie, Zhou, Qun-Yong, Gu, Dong-Feng, Li, Pei-Feng
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Molecular Bases of Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772234/
https://ncbi.nlm.nih.gov/pubmed/23873935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440453
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