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The Core Microprocessor Component DiGeorge Syndrome Critical Region 8 (DGCR8) Is a Nonspecific RNA-binding Protein

MicroRNA (miRNA) biogenesis follows a conserved succession of processing steps, beginning with the recognition and liberation of an miRNA-containing precursor miRNA hairpin from a large primary miRNA transcript (pri-miRNA) by the Microprocessor, which consists of the nuclear RNase III Drosha and the...

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Detalles Bibliográficos
Main Authors: Roth, Braden M., Ishimaru, Daniella, Hennig, Mirko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772224/
https://ncbi.nlm.nih.gov/pubmed/23893406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.446880
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