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Computational models of the JAK1/2-STAT1 signaling

Despite a conceptually simple mechanism of signaling, the JAK-STAT pathway exhibits considerable behavioral complexity. Computational pathway models are tools to investigate in detail signaling process. They integrate well with experimental studies, helping to explain molecular dynamics and to state...

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Detalhes bibliográficos
Main Authors: Gambin, Anna, Charzyńska, Agata, Ellert-Miklaszewska, Aleksandra, Rybiński, Mikołaj
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772111/
https://ncbi.nlm.nih.gov/pubmed/24069559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.24672
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