Influence of COMT val158met Genotype on the Depressed Brain during Emotional Processing and Working Memory

Major depressive disorder (MDD) has been associated with abnormal prefrontal-limbic interactions and altered catecholaminergic neurotransmission. The val158met polymorphism on the catechol-O-methyltransferase (COMT) gene has been shown to influence prefrontal cortex (PFC) activation during both emot...

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Bibliographic Details
Main Authors: Opmeer, Esther M., Kortekaas, Rudie, van Tol, Marie-José, van der Wee, Nic J. A., Woudstra, Saskia, van Buchem, Mark A., Penninx, Brenda W., Veltman, Dick J., Aleman, André
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772077/
https://ncbi.nlm.nih.gov/pubmed/24069183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073290
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