Structural Analysis of Peptide-Analogues of Human Zona Pellucida ZP1 Protein with Amyloidogenic Properties: Insights into Mammalian Zona Pellucida Formation

Zona pellucida (ZP) is an extracellular matrix surrounding and protecting mammalian and fish oocytes, which is responsible for sperm binding. Mammalian ZP consists of three to four glycoproteins, called ZP1, ZP2, ZP3, ZP4. These proteins polymerize into long interconnected filaments, through a commo...

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Bibliographic Details
Main Authors: Louros, Nikolaos N., Iconomidou, Vassiliki A., Giannelou, Polina, Hamodrakas, Stavros J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772061/
https://ncbi.nlm.nih.gov/pubmed/24069181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073258
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