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Tiam1 Transgenic Mice Display Increased Tumor Invasive and Metastatic Potential of Colorectal Cancer after 1,2-Dimethylhydrazine Treatment

BACKGROUND: T lymphoma invasion and metastasis 1 (Tiam1) is a potential modifier of tumor development and progression. Our previous study in vitro and in nude mice suggested a promotion role of Tiam1 on invasion and metastasis of colorectal cancer (CRC). In the present study, we generated Tiam1/C119...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Li-Na, Zhang, Qing-Ling, Li, Xin, Hua, Xing, Cui, Yan-Mei, Zhang, Nian-Jie, Liao, Wen-Ting, Ding, Yan-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771986/
https://ncbi.nlm.nih.gov/pubmed/24069171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073077
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