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Phase II Trial of Temsirolimus in Patients with Relapsed or Refractory Multiple Myeloma

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25 mg IV weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3–4 toxicity included fati...

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Detalhes bibliográficos
Main Authors: Farag, Sherif S., Zhang, Shuhong, Jansak, Buffy S., Wang, Xiaojing, Kraut, Eric, Chan, Kenneth, Dancey, Janet E., Grever, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771631/
https://ncbi.nlm.nih.gov/pubmed/19261329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.01.039
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