Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT

INTRODUCTION: We have previously developed a model that provides relative dosimetry estimates for targeted radionuclide therapy (TRT) agents. The whole body and tumor pharmacokinetic (PK) parameters of this model can be noninvasively measured with molecular imaging, providing a means of comparing po...

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Hlavní autoři: Grudzinski, Joseph J, Floberg, John M, Mudd, Sarah R, Jeffery, Justin J, Peterson, Eric T, Nomura, Alice, Burnette, Ronald R, Tomé, Wolfgang A, Weichert, Jamey P, Jeraj, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771497/
https://ncbi.nlm.nih.gov/pubmed/22398155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/57/6/1641
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