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Proteomic Analysis and Label-Free Quantification of the Large Clostridium difficile Toxins

Clostridium difficile is the leading cause of antibiotic-associated diarrhea in hospitals worldwide, due to hypervirulent epidemic strains with the ability to produce increased quantities of the large toxins TcdA and TcdB. Unfortunately, accurate quantification of TcdA and TcdB from different toxino...

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Detalhes bibliográficos
Main Authors: Moura, Hercules, Terilli, Rebecca R., Woolfitt, Adrian R., Williamson, Yulanda M., Wagner, Glauber, Blake, Thomas A., Solano, Maria I., Barr, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771451/
https://ncbi.nlm.nih.gov/pubmed/24066231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/293782
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