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Endocannabinoids in the Brainstem Modulate Dural Trigeminovascular Nociceptive Traffic via CB(1) and “Triptan” Receptors: Implications in Migraine

Activation and sensitization of trigeminovascular nociceptive pathways is believed to contribute to the neural substrate of the severe and throbbing nature of pain in migraine. Endocannabinoids, as well as being physiologically analgesic, are known to inhibit dural trigeminovascular nociceptive resp...

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Detalhes bibliográficos
Main Authors: Akerman, Simon, Holland, Philip R., Lasalandra, Michele P., Goadsby, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771033/
https://ncbi.nlm.nih.gov/pubmed/24027286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0943-13.2013
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