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Inhibition of human high affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced alzheimer’s disease-like symptoms

Disruption of copper homeostasis has been implicated in Alzheimer’s disease (AD) during the last two decades; however, whether copper is a friend or a foe is controversial. Within a genetically tractable Drosophila AD model, we manipulated the expression of human high affinity copper importer orthol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lang, Minglin, Fan, Qiangwang, Wang, Lei, Zheng, Yajun, Xiao, Guiran, Wang, Xiaoxi, Wang, Wei, Zhong, Yi, Zhou, Bing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770863/
https://ncbi.nlm.nih.gov/pubmed/23827522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.05.029
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