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Preparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery

PURPOSE: The aim of the present study was to prepare inhalable co-spray dried powders of salmon calcitonin loaded chitosan nanoparticles (sCT-CS-NPs) with mannitol and investigate pulmonary absorption in rats. METHODS: The sCT-CS-NPs were prepared by the ionic gelation method using sodium tripolypho...

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Detalhes bibliográficos
Main Authors: Sinsuebpol, Chutima, Chatchawalsaisin, Jittima, Kulvanich, Poj
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770519/
https://ncbi.nlm.nih.gov/pubmed/24039397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S47681
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