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A Dose-Escalation Study of Recombinant Human Interleukin-18 in Combination with Rituximab in Patients with Non-Hodgkin's Lymphoma
Interleukin-18 (IL-18) is an immunostimulatory cytokine with antitumor activity in preclinical models. Rituximab is a CD20 monoclonal antibody with activity against human B cell lymphomas. A phase I study of recombinant human (rh) IL-18 given with rituximab was performed in patients with CD20+ lymph...
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Hlavní autoři: | , , , , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
2013
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770482/ https://ncbi.nlm.nih.gov/pubmed/23799412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31829d7e2e |
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