Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1

Exposure of keratinocytes (KC) to ultraviolet (UV) radiation results in the initiation of apoptosis, a protective mechanism that eliminates cells harboring irreparable DNA damage. Hence, a manipulation of UV-induced apoptosis may significantly influence photocarcinogenesis. We have discovered that t...

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Detalhes bibliográficos
Main Authors: Frauenstein, K, Sydlik, U, Tigges, J, Majora, M, Wiek, C, Hanenberg, H, Abel, J, Esser, C, Fritsche, E, Krutmann, J, Haarmann-Stemmann, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770322/
https://ncbi.nlm.nih.gov/pubmed/23912710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.102
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