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Acute baclofen diminishes resting baseline blood flow to limbic structures: A perfusion fMRI study

BACKGROUND: Preclinical and clinical evidence show that the GABA B agonist, baclofen is a promising treatment for addictive disorders; however, until recently its mechanism of action in the human brain was unknown. In previous work we utilized a laboratory model that included a medication versus pla...

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Detalhes bibliográficos
Main Authors: Franklin, Teresa R., Shin, Joshua, Jagannathan, Kanchana, Suh, Jesse J., Detre, John A., O’Brien, Charles P., Childress, Anna Rose
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770303/
https://ncbi.nlm.nih.gov/pubmed/22513380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2012.03.016
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