Mitochondrial DNA Instability in Cells Lacking Aconitase Correlates with Iron Citrate Toxicity

Aconitase, the second enzyme of the tricarboxylic acid cycle encoded by ACO1 in the budding yeast Saccharomyces cerevisiae, catalyzes the conversion of citrate to isocitrate. aco1Δ results in mitochondrial DNA (mtDNA) instability. It has been proposed that Aco1 binds to mtDNA and mediates its mainte...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Farooq, Muhammad A., Pracheil, Tammy M., Dong, Zhejun, Xiao, Fei, Liu, Zhengchang
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770056/
https://ncbi.nlm.nih.gov/pubmed/24066190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/493536
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker