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Redesign of substrate specificity and identification of aminoglycoside binding residues of Eis from Mycobacterium tuberculosis

The upsurge of drug-resistant tuberculosis (TB) is an emerging global problem. Increased expression of the enhanced intracellular survival (Eis) protein is responsible for clinical resistance to aminoglycoside (AG) antibiotics in Mycobacterium tuberculosis. Eis from M. tuberculosis (Eis_Mtb) and fro...

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Bibliografski detalji
Glavni autori: Jennings, Benjamin C., Labby, Kristin J., Green, Keith D., Garneau-Tsodikova, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769965/
https://ncbi.nlm.nih.gov/pubmed/23837529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4002985
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