Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders

The hypoxic conditions at high altitudes present a challenge for survival, causing pressure for adaptation. Interestingly, many high-altitude denizens (particularly in the Andes) are maladapted, with a condition known as chronic mountain sickness (CMS) or Monge disease. To decode the genetic basis o...

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Hauptverfasser: Zhou, Dan, Udpa, Nitin, Ronen, Roy, Stobdan, Tsering, Liang, Junbin, Appenzeller, Otto, Zhao, Huiwen W., Yin, Yi, Du, Yuanping, Guo, Lixia, Cao, Rui, Wang, Yu, Jin, Xin, Huang, Chen, Jia, Wenlong, Cao, Dandan, Guo, Guangwu, Gamboa, Jorge L., Villafuerte, Francisco, Callacondo, David, Xue, Jin, Liu, Siqi, Frazer, Kelly A., Li, Yingrui, Bafna, Vineet, Haddad, Gabriel G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769925/
https://ncbi.nlm.nih.gov/pubmed/23954164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.07.011
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