Frequencies of Functional Polymorphisms in Three Pharmacokinetic Genes of Clinical Interest within the Admixed Puerto Rican Population

OBJECTIVE: This cross-sectional study was aimed at determining the allele frequencies for the CYP2C19*2, CYP2C19*3, CYP2D6*10 and PON1 (rs662) polymorphisms in the Puerto Rican population. The CYP2C19, CYP2D6 and PON1 genes are known to be associated with functional changes in drug metabolism and ac...

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Main Authors: Orengo-Mercado, Carmelo, Nieves, Bianca, López, Lizbeth, Vallés-Ortiz, Nabila, Renta, Jessicca Y., Santiago-Borrero, Pedro J., Cadilla, Carmen L., Duconge, Jorge
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769800/
https://ncbi.nlm.nih.gov/pubmed/24040574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2153-0645.1000113
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