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Manipulating the apoptotic pathway: potential therapeutics for cancer patients

This review summarizes the current state of scientific understanding of the apoptosis pathway, with a focus on the proteins involved in the pathway, their interactions and functions. This forms the rationale for detailing the preclinical and clinical pharmacology of drugs that modulate the pivotal p...

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Detalhes bibliográficos
Main Authors: Bates, Darcy J P, Lewis, Lionel D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769666/
https://ncbi.nlm.nih.gov/pubmed/23782006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12193
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