Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET

The fatty acids, n-butyric acid (BA), 4-phenylbutyric acid (PBA) and valproic acid (VPA, 2-propylpentanoic acid) have been used for many years in the treatment of a variety of CNS and peripheral organ diseases including cancer. New information that these drugs alter epigenetic processes through thei...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Sung Won, Hooker, Jacob M., Otto, Nicola, Win, Khaing, Muench, Lisa, Shea, Colleen, Carter, Pauline, King, Payton, Reid, Alicia E., Volkow, Nora D., Fowler, Joanna S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769509/
https://ncbi.nlm.nih.gov/pubmed/23906667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.06.007
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