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Phenotypes of Myopathy-Related Beta-Tropomyosin Mutants in Human and Mouse Tissue Cultures

Mutations in TPM2 result in a variety of myopathies characterised by variable clinical and morphological features. We used human and mouse cultured cells to study the effects of β-TM mutants. The mutants induced a range of phenotypes in human myoblasts, which generally changed upon differentiation t...

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Autori principali: Abdul-Hussein, Saba, Rahl, Karin, Moslemi, Ali-Reza, Tajsharghi, Homa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769345/
https://ncbi.nlm.nih.gov/pubmed/24039757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072396
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