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Multimolecular Analysis of Stable Immunological Synapses Reveals Sustained Recruitment and Sequential Assembly of Signaling Clusters

The formation of the immunological synapse between T cells and antigen-presenting cells (APC) begins within minutes of contact and can take hours for full T-cell activation. Although early phases of the synapse have been extensively studied for a select number of proteins, later phases have not yet...

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Detalhes bibliográficos
Main Authors: Philipsen, Lars, Engels, Thomas, Schilling, Kerstin, Gurbiel, Slavyana, Fischer, Klaus-Dieter, Tedford, Kerry, Schraven, Burkhart, Gunzer, Matthias, Reichardt, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769330/
https://ncbi.nlm.nih.gov/pubmed/23754785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.025205
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