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The Contribution of Orai(CRACM)1 and Orai(CRACM)2 Channels in Store-Operated Ca(2+) Entry and Mediator Release in Human Lung Mast Cells
BACKGROUND: The influx of extracellular Ca(2+) into mast cells is critical for the FcεR1-dependent release of preformed granule-derived mediators and newly synthesised autacoids and cytokines. The Orai(CRACM) ion channel family provide the major pathway through which this Ca(2+) influx occurs. Howev...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769304/ https://ncbi.nlm.nih.gov/pubmed/24040356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074895 |
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