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Effects of EZH2 Polymorphisms on Susceptibility to and Pathological Development of Hepatocellular Carcinoma

BACKGROUND: The enhancer of zeste 2 (EZH2) gene encodes the histone methyltransferase that is the catalytic component of the polycomb repressive complex-2, which initiates epigenetic silencing of genes. The expression level of EZH2 in hepatocellular carcinoma (HCC) is highly correlated with tumor pr...

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Autors principals: Yu, Yung-Luen, Su, Kuo-Jung, Hsieh, Yi-Hsien, Lee, Hsiang-Lin, Chen, Tzy-Yen, Hsiao, Pei-Ching, Yang, Shun-Fa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769270/
https://ncbi.nlm.nih.gov/pubmed/24040354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074870
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