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Multifactorial Understanding of Ion Abundance in Tandem Mass Spectrometry Experiments

In a bottom-up shotgun approach, the proteins of a mixture are enzymatically digested, separated, and analyzed via tandem mass spectrometry. The mass spectra relating fragment ion intensities (abundance) to the mass-to-charge are used to deduce the amino acid sequence and identify the peptides and p...

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Detalhes bibliográficos
Main Authors: Fazal, Zeeshan, Southey, Bruce R, Sweedler, Jonathan V., Rodriguez-Zas, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768159/
https://ncbi.nlm.nih.gov/pubmed/24031159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/jpb.1000256
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