Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer

The C-terminal binding protein (CtBP) is a NADH-dependent transcriptional repressor that links carbohydrate metabolism to epigenetic regulation by recruiting diverse histone modifying complexes to chromatin. Here, global profiling of CtBP in breast cancer cells reveals that it drives epithelial to m...

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Main Authors: Di, Li-Jun, Byun, Jung S., Wong, Madeline M., Wakano, Clay, Taylor, Tara, Bilke, Sven, Baek, Songjoon, Hunter, Kent, Yang, Howard, Lee, Maxwell, Zvosec, Celia, Khramtsova, Galina, Cheng, Fan, Perou, Charles M., Miller, C. Ryan, Raab, Rachel, Olopade, Olufunmilayo I., Gardner, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768144/
https://ncbi.nlm.nih.gov/pubmed/23385593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2438
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