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Engineered proteins with PUF scaffold to manipulate RNA metabolism

Pumilio/fem-3 mRNA binding factor (FBF) proteins are characterized by a sequence-specific RNA-binding domain. This unique single-stranded RNA recognition module, whose sequence specificity can be reprogrammed, has been fused with functional modules to engineer protein factors with various functions....

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Detalhes bibliográficos
Main Authors: Wang, Yang, Wang, Zefeng, Tanaka Hall, Traci M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768134/
https://ncbi.nlm.nih.gov/pubmed/23731364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12367
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