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Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity
Growth hormone (GH) is a key determinant of postnatal growth and plays an important role in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling delays aging and remarkably extends longevity in laboratory mice. In GH-deficient and GH-resistant animals, the “health...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3768106/ https://ncbi.nlm.nih.gov/pubmed/23589828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00006.2012 |
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