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Epigenetics and the Control of the Collecting Duct Epithelial Sodium Channel
The apical membrane epithelial Na(+) channel subunit (ENaC) in series with the basolateral Na(+)/K(+)-ATPase mediates collecting duct Na(+) reabsorption. Aldosterone induces αENaC gene transcription, which appears to be rate limiting for ENaC activity in this segment. While this response has long be...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767935/ https://ncbi.nlm.nih.gov/pubmed/24011580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2013.05.010 |
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