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Epigenetics and the Control of the Collecting Duct Epithelial Sodium Channel

The apical membrane epithelial Na(+) channel subunit (ENaC) in series with the basolateral Na(+)/K(+)-ATPase mediates collecting duct Na(+) reabsorption. Aldosterone induces αENaC gene transcription, which appears to be rate limiting for ENaC activity in this segment. While this response has long be...

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Bibliografiske detaljer
Hovedforfatter: Kone, Bruce C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767935/
https://ncbi.nlm.nih.gov/pubmed/24011580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2013.05.010
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