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LPS-Induced proNGF Synthesis and Release in the N9 and BV2 Microglial Cells: A New Pathway Underling Microglial Toxicity in Neuroinflammation

PURPOSE: While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duan, Li, Chen, Bei-Yu, Sun, Xiao-Long, Luo, Zhuo-Jing, Rao, Zhi-Ren, Wang, Jing-Jie, Chen, Liang-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767823/
https://ncbi.nlm.nih.gov/pubmed/24040063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073768
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