The Diuretic Torasemide Does Not Prevent Aldosterone-Mediated Mineralocorticoid Receptor Activation in Cardiomyocytes

Aldosterone binds to the mineralocorticoid receptor (MR) and exerts pleiotropic effects beyond enhancing renal sodium reabsorption. Excessive mineralocorticoid signaling is deleterious during the evolution of cardiac failure, as evidenced by the benefits provided by adding MR antagonists (MRA) to st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gravez, Basile, Tarjus, Antoine, Jimenez-Canino, Ruben, El Moghrabi, Soumaya, Messaoudi, Smail, de la Rosa, Diego Alvarez, Jaisser, Frederic
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767808/
https://ncbi.nlm.nih.gov/pubmed/24040049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073737
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