Paraquat Poisoning Induces TNF-α-Dependent iNOS/NO Mediated Hyporesponsiveness of the Aorta to Vasoconstrictors in Rats

Paraquat is a toxic herbicide that may induce acute lung injury, circulatory failure and death. The present work aimed at investigating whether there is systemic inflammation and vascular dysfunction after paraquat exposure and whether these parameters were related. There was neutrophilia and accumu...

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Bibliographic Details
Main Authors: Aires, Rosária D., Capettini, Luciano S. A., Silva, Josiane F., Rodrigues-Machado, Maria da Glória, Pinho, Vanessa, Teixeira, Mauro M., Cortes, Steyner F., Lemos, Virginia S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767802/
https://ncbi.nlm.nih.gov/pubmed/24039983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073562
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