Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells

Keratin 23 (KRT23) is strongly expressed in colon adenocarcinomas but absent in normal colon mucosa. Array based methylation profiling of 40 colon samples showed that the promoter of KRT23 was methylated in normal colon mucosa, while hypomethylated in most adenocarcinomas. Promoter methylation corre...

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Main Authors: Birkenkamp-Demtröder, Karin, Hahn, Stephan A., Mansilla, Francisco, Thorsen, Kasper, Maghnouj, Abdelouahid, Christensen, Rikke, Øster, Bodil, Ørntoft, Torben Falck
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767798/
https://ncbi.nlm.nih.gov/pubmed/24039993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073593
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