The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression

Cells use common signaling molecules for the selective control of downstream gene expression and cell-fate decisions. The relationship between signaling molecules and downstream gene expression and cellular phenotypes is a multiple-input and multiple-output (MIMO) system and is difficult to understa...

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Detalhes bibliográficos
Main Authors: Akimoto, Yuki, Yugi, Katsuyuki, Uda, Shinsuke, Kudo, Takamasa, Komori, Yasunori, Kubota, Hiroyuki, Kuroda, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767677/
https://ncbi.nlm.nih.gov/pubmed/24039801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072780
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