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Antigen-Specific Suppression and Immunological Synapse Formation by Regulatory T Cells Require the Mst1 Kinase

Although the cell-to-cell contact between CD4(+)Foxp3(+) regulatory T (Treg) and their target cells is important for the suppressor function of Treg cells, the regulation of this process is not well understood. Here we show that the Mst1 kinase plays a critical role in the suppressor function of Tre...

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Detalhes bibliográficos
Main Authors: Tomiyama, Takashi, Ueda, Yoshihiro, Katakai, Tomoya, Kondo, Naoyuki, Okazaki, Kazuichi, Kinashi, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767606/
https://ncbi.nlm.nih.gov/pubmed/24040101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073874
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