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Axial interactions in the mixed-valent Cu(A) active site and role of the axial methionine in electron transfer

Within Cu-containing electron transfer active sites, the role of the axial ligand in type 1 sites is well defined, yet its role in the binuclear mixed-valent Cu(A) sites is less clear. Recently, the mutation of the axial Met to Leu in a Cu(A) site engineered into azurin (Cu(A) Az) was found to have...

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Autors principals: Tsai, Ming-Li, Hadt, Ryan G., Marshall, Nicholas M., Wilson, Tiffany D., Lu, Yi, Solomon, Edward I.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767567/
https://ncbi.nlm.nih.gov/pubmed/23964128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314242110
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