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Single point mutations in ATP synthase compensate for mitochondrial genome loss in trypanosomes

Viability of the tsetse fly-transmitted African trypanosome Trypanosoma brucei depends on maintenance and expression of its kinetoplast (kDNA), the mitochondrial genome of this parasite and a putative target for veterinary and human antitrypanosomatid drugs. However, the closely related animal patho...

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Detalhes bibliográficos
Main Authors: Dean, Samuel, Gould, Matthew K., Dewar, Caroline E., Schnaufer, Achim C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767566/
https://ncbi.nlm.nih.gov/pubmed/23959897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305404110
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