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Dosage Compensation of the Sex Chromosomes

Differentiated sex chromosomes evolved because of suppressed recombination once sex became genetically controlled. In XX/XY and ZZ/ZW systems, the heterogametic sex became partially aneuploid after degeneration of the Y or W. Often, aneuploidy causes abnormal levels of gene expression throughout the...

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Autor principal: Disteche, Christine M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767307/
https://ncbi.nlm.nih.gov/pubmed/22974302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-110711-155454
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