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The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition

Apocynin is widely used as an inhibitor of the NADPH oxidase. Since myeloperoxidase (MPO) has been considered as essential for the mechanism of action of apocynin, here we used cells with different levels of MPO and compared their sensitivity to apocynin. HL-60 cells were differentiated with DMSO or...

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Bibliographic Details
Main Authors: de Almeida, Ana Carolina, dos Santos Vilela, Maria Marluce, Condino-Neto, Antonio, Ximenes, Valdecir F.
Format: Artigo
Language:Inglês
Published: International Scholarly Research Network 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767205/
https://ncbi.nlm.nih.gov/pubmed/24049643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/260453
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